This manual provides therapists with up-to-date information about how to implement TF-CBT for trauma-impacted LGBTQ youth, and also includes valuable resources from the Family Acceptance Project (FAP) ™ . We are extremely grateful to Dr. Caitlin Ryan of the FAP for her generous contributions to this project, and to the clinicians who participated in the NCTSN-sponsored TF-CBT LGBTQ Learning Community to develop this manual. Pilot data from that project support the effectiveness of the TF-CBT applications described in this manual for improving PTSD symptoms in trauma-impacted LGBTQ youth.